The AMDRT Study

For "Wet" Macular Degeneration

 

Dear Colleague:

This is to update you on the status of a clinical trial for radiation therapy for age-related macular degeneration. The National Eye Institute, through the National Institutes of Health, has awarded a grant to fund a pilot study evaluating the role of external beam radiation therapy in age-related macular degeneration. The grant is being administered through the University of Pennsylvania, Scheie Eye Institute. Approximately 13 centers from around the country are participating.

The New York AMDRT Center is an approved site which can enroll patients immediately. Eligible patients are those with a diagnosis of the "wet type" of age-related macular degeneration.

There are 2 AMDRT Studies:

New Subfoveal CNV Study: This includes patients with angiographic evidence of subfoveal CNV that is not amenable to laser treatment or to photodynamic therapy according to published guidelines from clinical trials.

Recurrent CNV Study: This includes patients who have been treated with laser, but show evidence of persistent or recurrent CNV on fluorescein angiography and who are not eligible for laser treatment or photodynamic therapy according to published guidelines from clinical trials.

Patients who are eligible for either study after providing informed consent, will be randomized to receiving external beam radiation therapy versus no radiation.

Chairman:
Stuart L. Fine, MD

Coordinating Center:
Ellen Peskin, MA
Maureen Maguire, PhD

Principal Investigators:
C. Leland Rogers, MD - Center for Cancer Research and Education - Phoenix, Arizona.
Christine Flaxel, MD - Doheny Eye Institute, Los Angeles, California
Robert Johnson, MD - Schatz, McDonald, Johnson & Ai, San Francisco, California
Thomas Aaberg, Jr., MD - Emory Eye Center, Atlanta, Georgia
Dennis Marcus, MD - Medical College of Georgia, Augusta, Georgia
Jack Cohen, MD - Rush Eye Center, Chicago, Illinois
John Minturn, MD - Midwest Eye Institute, Indianapolis, Indiana
Lawrence Arend, MD - Ochsner Clinic, New Orleans, Louisiana
Paul T. Finger, MD - The New York AMDRT Center, New York City, New York
Louis Chorich III, MD - Ohio State University, Columbus, Ohio
Alexander Brucker, MD - Scheie Eye Institute, Philadelphia, Pennsylvania
Karl Olsen, MD - University of Pittsburgh, Pittsburgh, Pennsylvania
David Weissgold, MD - University of Vermont, Burlington, Vermont

Reading Center:
Albert Maguire, MD
Judy Alexander
Kathy McWilliams

Radiological Physics Center:
David Followill, PhD

National Eye Institute:
Mary Frances Cotch, PhD

If you are a doctor and have patients who are eligible for this study, please contact Ms. Ellen Peskin at 1-215-615-1505 or Click Here.

If you are a patient ask your doctor if your are eligible and contact us to find a doctor near you.

Thank you for your assistance!

For more information contact: Paul T. Finger, MD.

 

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